Microcystins hepatotoxic heptapeptides in German fresh water bodies
نویسندگان
چکیده
منابع مشابه
Genes coding for hepatotoxic heptapeptides (microcystins) in the cyanobacterium Anabaena strain 90.
The cluster of microcystin synthetase genes from Anabaena strain 90 was sequenced and characterized. The total size of the region is 55.4 kb, and the genes are organized in three putative operons. The first operon (mcyA-mcyB-mcyC) is transcribed in the opposite direction from the second operon (mcyG-mcyD-mcyJ-mcyE-mcyF-mcyI) and the third operon (mcyH). The genes mcyA, mcyB, and mcyC encode non...
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An acute toxicity experiment was conducted to examine the distribution and depuration of microcystins (MCs) in crucian carp (Carassius aurutus) tissues. Fish were injected intraperitoneally with extracted MCs at a dose of 200 microg MC-LR (where L=leucine and R=arginine) equivalent/kg body weight. Microcystin concentrations in various tissues and aquaria water were analyzed at 1, 3, 12, 24, and...
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In vivo visualization of kidney and liver damage by Magnetic Resonance Imaging (MRI) may offer an advantage when there is a need for a simple, non-invasive and rapid method for screening of the effects of potential nephrotoxic and hepatotoxic substances in chronic experiments. Here, we used MRI for monitoring chronic intoxication with microcystins (MCs) in rat. Male adult Wistar rats were treat...
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ژورنال
عنوان ژورنال: Environmental Toxicology
سال: 1999
ISSN: 1520-4081,1522-7278
DOI: 10.1002/(sici)1522-7278(199905)14:2<291::aid-tox11>3.3.co;2-5